Children with Severe Malnutrition: Can Those at Highest Risk of Death Be Identified with the WHO Protocol?

diciembre 30, 2006

PLoS Medicine
Kathryn Maitland1, James A. Berkley1, Mohammed Shebbe1, Norbert Peshu1, Michael English1, Charles R. J. C. Newton

Background

With strict adherence to international recommended treatment guidelines, the case fatality for severe malnutrition ought to be less than 5%. In African hospitals, fatality rates of 20% are common and are often attributed to poor training and faulty case management. Improving outcome will depend upon the identification of those at greatest risk and targeting limited health resources. We retrospectively examined the major risk factors associated with early (<48 h) and late in-hospital death in children with severe malnutrition with the aim of identifying admission features that could distinguish a high-risk group in relation to the World Health Organization (WHO) guidelines.

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